Villains of Summer!
What's Her Deal? Weakling no more, Dr. Doom turned Skeeter MacPherson into the mighty Titania for some good ol' fashioned throw down against the Marvel heroes. I think her name is taken more because it's like "Titan" than it is because it's like the fairy queen from Shakespeare, but because she shares the name of our famed character of A Midsummer Night's Dream, Titania is a perfect, if oblique, Villain of Summer!
What Should She Do? Well, as we speak she's throwing down as one of The Worthy, agents of The Serpent, and causing massive mayhem. But other than than, she is always good for a one-off tussle with the likes of She-Hulk and Spider-Man. If you want to use her more purposefully, her backstory contains themes of self-esteem, "might makes right", and self-indulgence. That would play perfectly with Ms. Marvel and the new Power Man/Iron Fist combo, or even folks like the Runaways and Power Pack.
Of course, you could always run with the oblique reference, and have her fight with Alpha Flight's Puck, and see if anyone other than me would pick up on it.